https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52044 Wed 27 Sep 2023 10:07:51 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22760 Wed 11 Apr 2018 09:54:42 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31060 14 days) exposure to a PDA were compared to control infants without a PDA. Results: Thirty out of 189 infants had prolonged exposure to a PDA. The left heart remodeled to a larger and more spherical shape and thus significantly increased in volume. Most changes occurred in the first 4 weeks, plateaued, and then returned to control values. Systolic function and estimates of filling pressure increased and effective arterial elastance reduced with a PDA, however contractility was unchanged. Wall thickness increased after 4 weeks of increased volume exposure. Conclusion: The preterm PDA induces early and significant remodeling of the left heart. A compensated cardiac physiology was seen with preserved systolic function, suggesting adaptive rather than pathological remodeling changes with prolonged exposure to a PDA.]]> Wed 10 Nov 2021 15:14:02 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38110 Wed 04 Aug 2021 09:52:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40860 Tue 19 Jul 2022 13:56:28 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38193 Thu 26 Aug 2021 09:23:08 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43241 Thu 15 Sep 2022 10:10:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9679 Sat 24 Mar 2018 08:39:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18870 Sat 24 Mar 2018 08:03:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18369 Sat 24 Mar 2018 07:52:38 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46963 R +0.42, +0.50, +0.47, +0.50, all P < 0.01), and transmitral Vti (R +0.37, P < 0.01). PVFT correlated negatively with E, EA, and Ee' (R -0.42, -0.47, -0.47, all P < 0.01). Conclusion: Left ventricle vortex formation can be analyzed with two-dimensional BSI and has the potential to complement existing parameters of cardiac health.]]> Mon 12 Dec 2022 15:23:31 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42822 Mon 05 Sep 2022 11:49:26 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42185 P<0.001). GAL3 levels were higher in MHD‐POS versus MHD‐NEG patients (7.7±2.3 versus 6.3±1.9 ng/mL, respectively; P<0.001). Both GAL3 and FSTL3 levels correlated with diastolic dysfunction and increased pulmonary artery systolic pressure but not with left ventricular mass. In multivariate models including all 3 biomarkers, only GAL3 remained associated with MHD (odds ratio: 1.30; 95% CI, 1.01–1.68; P=0.04). Conclusions: In young obese individuals without known cardiovascular disease, GAL3 is associated with the presence of preclinical MHD. GAL3 may be useful in screening for preclinical MHD and identifying individuals with increased risk of progression to obesity‐related heart failure with preserved ejection fraction.]]> Fri 26 Aug 2022 08:26:42 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46160 Fri 11 Nov 2022 19:20:09 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49806 Fri 02 Jun 2023 17:00:09 AEST ]]>